BDBM50256480 CHEMBL466397::N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-4-(4-(4-(methylsulfonyl)piperazin-1-yl)piperidin-1-yl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-2-methoxybenzamide
SMILES CCc1cc(Nc2nccc(n2)-c2c(nc3ccccn23)-c2ccc(OC)c(c2)C(=O)Nc2c(F)cccc2F)c(OC)cc1N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O
InChI Key InChIKey=MOSKATHMXWSZTQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50256480
Affinity DataKi: 1.30nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of GST-tagged insulin receptor expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human insulin receptor autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair