BDBM50257255 2-{1-[3-(6-Benzyl-1-propyl-naphthalen-2-yloxy)-propyl]-1H-indol-5-yloxy}-2-methyl-propionic acid::CHEMBL523334

SMILES Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1ccnc(Nc2ccccc2C(C)(C)C)n1

InChI Key InChIKey=SCMAGMDUOPURTJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257255   

LigandChemical structure of BindingDB Monomer ID 50257255BDBM50257255(CHEMBL6078540)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50257255BDBM50257255(CHEMBL6078540)
Affinity DataIC50: 210nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50257255BDBM50257255(CHEMBL6078540)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed