BDBM50257601 CHEMBL4089955

SMILES Cc1cc(Oc2ccc(cc2F)-c2ccn3c(CC4CC4)nnc3c2C(F)(F)F)cc(C)n1

InChI Key InChIKey=AGALLFGKUGSMHT-UHFFFAOYSA-N

Data  1 KI  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257601   

TargetMetabotropic glutamate receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257601BDBM50257601(CHEMBL4089955)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257601BDBM50257601(CHEMBL4089955)
Affinity DataKd:  12nMAssay Description:Binding affinity to human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Leiden University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50257601BDBM50257601(CHEMBL4089955)
Affinity DataEC50:  65nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed