BDBM50257698 CHEMBL522849::N-(5-((cyclohexyl(methyl)amino)methyl)-1-(2-hydroxy-2-methylpropyl)-1H-benzo[d]imidazol-2(3H)-ylidene)-5-(1H-pyrazol-4-yl)thiophene-2-carboxamide
SMILES CN(Cc1ccc2n(CC(C)(C)O)c(NC(=O)c3ccc(s3)-c3cn[nH]c3)nc2c1)C1CCCCC1
InChI Key InChIKey=NBGLUPSFCNIDOO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50257698
Affinity DataIC50: 2nMAssay Description:Binding affinity to ITK (unknown origin) by DELFIA-based molecular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human ITK expressed in BTK deficient DT40 cells assessed as inhibition of B cell receptor-stimulated calcium influxMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of ITK (unknown origin) in presence of 1 mM ATPMore data for this Ligand-Target Pair