BDBM50258082 6-fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide::CHEMBL495018::cid_44573641

SMILES O=C(NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc2cc(F)ccc2c1

InChI Key InChIKey=RNRZZDOZBGNGSH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258082   

TargetPhospholipase D1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258082BDBM50258082(CHEMBL495018 | cid_44573641 | 6-fluoro-N-(2-(4-(2-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258082BDBM50258082(CHEMBL495018 | cid_44573641 | 6-fluoro-N-(2-(4-(2-...)
Affinity DataIC50: 120nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258082BDBM50258082(CHEMBL495018 | cid_44573641 | 6-fluoro-N-(2-(4-(2-...)
Affinity DataIC50: 850nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258082BDBM50258082(CHEMBL495018 | cid_44573641 | 6-fluoro-N-(2-(4-(2-...)
Affinity DataIC50: 850nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay