BDBM50258453 3-(2-chloro-4-((5-isopropyl-3-((2,4,6-trichlorophenoxy)methyl)isoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL466641

SMILES CC(C)c1onc(COc2c(Cl)cc(Cl)cc2Cl)c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=CEWFKCPXHRZOEO-VOTSOKGWSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258453   

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258453(3-(2-chloro-4-((5-isopropyl-3-((2,4,6-trichlorophe...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258453(3-(2-chloro-4-((5-isopropyl-3-((2,4,6-trichlorophe...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed