BDBM50258484 3-(2-chloro-4-((3-((4-chloro-2,6-dimethylphenoxy)methyl)-5-isopropylisoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL466232

SMILES CC(C)c1onc(COc2c(C)cc(Cl)cc2C)c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=QCSZIGKHCCXOKT-CMDGGOBGSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258484   

TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258484(3-(2-chloro-4-((3-((4-chloro-2,6-dimethylphenoxy)m...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258484(3-(2-chloro-4-((3-((4-chloro-2,6-dimethylphenoxy)m...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed