BDBM50258511 3-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-(1-methyl-1H-tetrazol-5-yl)isoxazol-4-yl)methoxy)styryl)benzoic acid::CHEMBL468734

SMILES CC(C)c1onc(CSc2nnnn2C)c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1

InChI Key InChIKey=MGRUGMCSOGZDHZ-BQYQJAHWSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258511   

TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258511(3-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-(1-methyl...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human FXR transfected in african green monkey CV1 cells by luciferase reporter gene transient transfection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50258511(3-(2-chloro-4-((3-(2,6-dichlorophenyl)-5-(1-methyl...)
Affinity DataEC50:  930nMAssay Description:Agonist activity at human FXR assessed as SRC1 peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed