BDBM50259099 CHEMBL3084527::endo-N-((8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-azabicyclo[3.2.1]octan-3-yl)methyl)acetamide

SMILES CC(=O)NC[C@]1(c2ccccc2)C[C@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=XCYVMPGKVNMSEA-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259099   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259099BDBM50259099(endo-N-((8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259099BDBM50259099(endo-N-((8-(bis(2-chlorophenyl)methyl)-3-phenyl-8-...)
Affinity DataEC50:  269nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed