BDBM50259189 CHEMBL3084536::endo-8-(bis(2-chlorophenyl)methyl)-3-(5-cyanopyridin-2-yl)-8-azabicyclo[3.2.1]octane-3-carboxamide

SMILES N#Cc1ccc([C@@]2(C(N)=O)C[C@H]3CC[C@@H](C2)N3C(c2ccccc2Cl)c2ccccc2Cl)nc1

InChI Key InChIKey=AZUMDPMNGBWFOH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259189   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259189BDBM50259189(endo-8-(bis(2-chlorophenyl)methyl)-3-(5-cyanopyrid...)
Affinity DataKi:  75nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259189BDBM50259189(endo-8-(bis(2-chlorophenyl)methyl)-3-(5-cyanopyrid...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed