BDBM50259579 CHEMBL3084559::endo-8-(bis(2-chlorophenyl)methyl)-3-(pyridin-3-yl)-8-azabicyclo[3.2.1]octane-3-carboxamide

SMILES NC(=O)[C@]1(c2cccnc2)C[C@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=VVCRMEISGQLUSE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259579   

TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259579BDBM50259579(endo-8-(bis(2-chlorophenyl)methyl)-3-(pyridin-3-yl...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259579BDBM50259579(endo-8-(bis(2-chlorophenyl)methyl)-3-(pyridin-3-yl...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed