BDBM50259594 CHEMBL4068321

SMILES Brc1ccc(COc2ccc3ccc(=O)oc3c2)cc1

InChI Key InChIKey=XBQHFKZKJXERFF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259594   

TargetAmine oxidase [flavin-containing] B(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259594(CHEMBL4068321)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259594(CHEMBL4068321)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259594(CHEMBL4068321)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE using S-butylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259594(CHEMBL4068321)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed