BDBM50259839 CHEMBL4100677

SMILES Oc1c(Br)cc2cc(-c3nnn[nH]3)c(=O)oc2c1[N+]([O-])=O

InChI Key InChIKey=AQJFPDDDKBWBAG-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50259839   

TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataKi:  51nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataIC50:  8.60nMAssay Description:Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  3nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells incubated for 1 hr by DMR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  197nMAssay Description:Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed