BDBM50259913 CHEMBL4082605

SMILES CN1C(Nc2nc3ccc(Cl)nc3s2)=NCC12CN1CCC2CC1

InChI Key InChIKey=KJBHTEPFYURRRS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259913   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259913BDBM50259913(CHEMBL4082605)
Affinity DataEC50:  550nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259913BDBM50259913(CHEMBL4082605)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed