BDBM50260078 CHEMBL4095826::US10689390, Compound 26::US11319326, Compound 26

SMILES CCNC(=O)CC1N=C(C2CCCCC2)c2cc(OC)ccc2-c2cn(C)c(=O)cc12

InChI Key InChIKey=UVTKTBNWUZYOKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260078   

TargetBromodomain-containing protein 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50260078(CHEMBL4095826 | US10689390, Compound 26 | US113193...)
Affinity DataIC50:  2nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) using biotinylated substrate after 1 hr by AlphaLisa assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM50260078(CHEMBL4095826 | US10689390, Compound 26 | US113193...)
Affinity DataIC50:  2nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBromodomain-containing protein 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50260078(CHEMBL4095826 | US10689390, Compound 26 | US113193...)
Affinity DataIC50:  2nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In DepthDetails US Patent