BDBM50260145 CHEMBL4070290

SMILES O=C(Cc1cc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)ccc1F)NCCc1cn[nH]c1

InChI Key InChIKey=UWGQNVKEQMCXMS-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260145   

TargetBeta-adrenergic receptor kinase 1(Bovine)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260145BDBM50260145(CHEMBL4070290)
Affinity DataIC50: 630nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG protein-coupled receptor kinase 5(Bovine)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260145BDBM50260145(CHEMBL4070290)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetRhodopsin kinase GRK1(Bovine)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260145BDBM50260145(CHEMBL4070290)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK1 (1 to 535 residues) after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed