BDBM50260279 (R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(phenyl)methanone::CHEMBL522806::[(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE

SMILES CC1=C(C(=O)c2ccccc2)[C@@H](c2cccc(O)c2)NC(=S)N1C

InChI Key InChIKey=JGBBILLMZPWNFU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260279   

TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260279BDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260279BDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 110nMAssay Description:Inhibition of basal ATPase activity of human Eg5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260279BDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of microtubule-stimulated human Eg5 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260279BDBM50260279((R)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed