BDBM50260713 (R)-4-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-amino-2-phenylethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzyl 2-aminoacetate::CHEMBL499307

SMILES NCC(=O)OCc1ccc(cc1)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O

InChI Key InChIKey=SYBXHLIANYBTCO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260713   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50260713((R)-4-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2...)
Affinity DataKi:  77nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50260713((R)-4-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2...)
Affinity DataIC50: 670nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed