BDBM50260924 CHEMBL4104344

SMILES Cc1ccc(cc1)-c1cnc(N)c(c1)-c1cnn(C)c1

InChI Key InChIKey=JBNFPUPGGQWNBG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260924   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50260924(CHEMBL4104344)Copy SMILESCopy InChI

Affinity DataIC50:  6.70E+3nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in Mouse L(tk-) cell membranes incubated for 120 mins by scintillation count...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
H. Lundbeck

Curated by ChEMBL

LigandBDBM50260924(CHEMBL4104344)Copy SMILESCopy InChI

Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL