BDBM50261300 CHEMBL4084362

SMILES Fc1ccc(nc1)-c1nc2CN(CCc2o1)C(=O)c1cc(F)cc(c1)C#N

InChI Key InChIKey=HNFIYCVEOIXWEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261300   

TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261300(CHEMBL4084362)
Affinity DataIC50: 403nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed