BDBM50261589 CHEMBL4081152

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(Cn1ccnc1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=IKZNOPCOTMWDLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261589   

Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261589(CHEMBL4081152)
Affinity DataIC50: 95nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261589(CHEMBL4081152)
Affinity DataIC50: 4.48E+3nMAssay Description:Inhibition of human CYP24A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed