BDBM50262063 4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide::CHEMBL469220

SMILES Cc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=ZNRYVLKGZXYUQQ-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50262063   

TargetCarbonic anhydrase 12(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 5B, mitochondrial(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  10.6nMAssay Description:Inhibition of human recombinant CA5B by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 5A, mitochondrial(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  12.8nMAssay Description:Inhibition of human recombinant CA5A by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  18.6nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 9(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  22nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  176nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  368nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant COX2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50262063(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of ovine COX1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed