BDBM50262072 CHEMBL4079770

SMILES CNC[C@H]1CC[C@H](C(=O)N2C[C@@H](c3ccc(C#N)cc3)[C@H](c3ccc4c(cnn4C)c3)C2)CC1

InChI Key InChIKey=IFFHYEXGKXIESO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262072   

TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262072BDBM50262072(CHEMBL4079770)
Affinity DataKd:  540nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262072BDBM50262072(CHEMBL4079770)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed