BDBM50262073 CHEMBL4101423

SMILES Cn1ncc2cc([C@@H]3CN(C(=O)[C@H]4CC[C@H](N)CC4)C[C@H]3c3ccc(C#N)cc3)ccc21

InChI Key InChIKey=MQXNDHPZBPNEFV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262073   

TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262073BDBM50262073(CHEMBL4101423)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Manchester

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262073BDBM50262073(CHEMBL4101423)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed