BDBM50262176 6,6-dimethyl-2-(6-(2-methyl-1H-imidazol-4-yl)-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one::CHEMBL467395

SMILES Cc1nc(c[nH]1)-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1

InChI Key InChIKey=KLKZGMKQDCBAEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262176   

LigandPNGBDBM50262176(6,6-dimethyl-2-(6-(2-methyl-1H-imidazol-4-yl)-2,3-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of PI3K deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262176(6,6-dimethyl-2-(6-(2-methyl-1H-imidazol-4-yl)-2,3-...)
Affinity DataIC50: 107nMAssay Description:Inhibition of PI3K gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262176(6,6-dimethyl-2-(6-(2-methyl-1H-imidazol-4-yl)-2,3-...)
Affinity DataIC50: 325nMAssay Description:Inhibition of PI3K betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262176(6,6-dimethyl-2-(6-(2-methyl-1H-imidazol-4-yl)-2,3-...)
Affinity DataIC50: 636nMAssay Description:Inhibition of PI3K alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed