BDBM50262621 CHEMBL476942::N-(2-Isopropyl-benzyl)-N-(S)-pyrrolidin-3-yl-isobutyramide

SMILES CC(C)C(=O)N(Cc1ccccc1C(C)C)[C@H]1CCNC1

InChI Key InChIKey=XFORZXNXAQQOKS-INIZCTEOSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262621   

LigandPNGBDBM50262621(CHEMBL476942 | N-(2-Isopropyl-benzyl)-N-(S)-pyrrol...)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262621(CHEMBL476942 | N-(2-Isopropyl-benzyl)-N-(S)-pyrrol...)
Affinity DataKi:  544nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262621(CHEMBL476942 | N-(2-Isopropyl-benzyl)-N-(S)-pyrrol...)
Affinity DataKi:  3.41E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed