BDBM50262626 CHEMBL515936::Ethanesulfonic acid biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amide

SMILES CCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1

InChI Key InChIKey=JTFGLXWULCGHRY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262626   

LigandPNGBDBM50262626(Ethanesulfonic acid biphenyl-2-ylmethyl-(S)-pyrrol...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262626(Ethanesulfonic acid biphenyl-2-ylmethyl-(S)-pyrrol...)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262626(Ethanesulfonic acid biphenyl-2-ylmethyl-(S)-pyrrol...)
Affinity DataKi:  2.76E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262626(Ethanesulfonic acid biphenyl-2-ylmethyl-(S)-pyrrol...)
Affinity DataKi:  5.62E+3nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed