BDBM50262674 CHEMBL476527::N-(S)-Pyrrolidin-3-yl-N-(2-trifluoromethyl-benzyl)-isobutyramide

SMILES CC(C)C(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1

InChI Key InChIKey=FYDXJUSDGLWNFV-ZDUSSCGKSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262674   

LigandPNGBDBM50262674(CHEMBL476527 | N-(S)-Pyrrolidin-3-yl-N-(2-trifluor...)
Affinity DataKi:  63nMAssay Description:Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262674(CHEMBL476527 | N-(S)-Pyrrolidin-3-yl-N-(2-trifluor...)
Affinity DataKi:  133nMAssay Description:Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed