BDBM50262846 CHEMBL4064598

SMILES COc1ccccc1CN(CCCN1C(=O)c2ccccc2C1=O)CC#C

InChI Key InChIKey=NKQRLCDALRZSDY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262846   

TargetAcetylcholinesterase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50262846(CHEMBL4064598)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of rat cortex homogenate AChE using acetylthiocholine chloride as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50262846(CHEMBL4064598)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50262846(CHEMBL4064598)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50262846(CHEMBL4064598)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50262846(CHEMBL4064598)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2020
Entry Details Article
PubMed