BDBM50262864 CHEMBL477582::Furan-2-carboxylic acid [4'-(cyclopropylmethyl-carbamoyl)-6-methyl-biphenyl-3-yl]-amide

SMILES Cc1ccc(NC(=O)c2ccco2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key InChIKey=BKWXTFBEQWOLSP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262864   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262864(CHEMBL477582 | Furan-2-carboxylic acid [4'-(cyclop...)
Affinity DataKi:  25nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262864(CHEMBL477582 | Furan-2-carboxylic acid [4'-(cyclop...)
Affinity DataIC50:  160nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed