BDBM50263347 1-(6-aminopyrimidin-4-yl)-N-(2-bromo-4,6-dimethylphenyl)-1H-benzo[d]imidazol-2-amine::CHEMBL477612

SMILES Cc1cc(C)c(Nc2nc3ccccc3n2-c2cc(N)ncn2)c(Br)c1

InChI Key InChIKey=AMXFBJCSYDYPNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263347   

TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263347(1-(6-aminopyrimidin-4-yl)-N-(2-bromo-4,6-dimethylp...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of TEL fused Lck (unknown origin)-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263347(1-(6-aminopyrimidin-4-yl)-N-(2-bromo-4,6-dimethylp...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of Lck by lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed