BDBM50263357 CHEMBL478434::trans-7'-Methoxy-3'-oxo-3'H-spiro[cyclohexane-1,1'-isobenzofuran]-4-carboxylic acid methyl-(2-piperidin-1-yl-ethyl)-amide

SMILES COc1cccc2c1[C@]1(CC[C@@H](C(=O)N(C)CCN3CCCCC3)CC1)OC2=O

InChI Key InChIKey=HTAUIWGHWGTTSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263357   

TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263357BDBM50263357(trans-7'-Methoxy-3'-oxo-3'H-spiro[cyclohexane-1,1'...)
Affinity DataIC50: 3.60nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of (R)-alpha-methylhistamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed