BDBM50263413 2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']bipiperidinyl-1'-ylmethyl]-benzonitrile::CHEMBL476990

SMILES O=c1[nH]c2ccccc2n1C1CCN(CC1)C1CCN(Cc2ccccc2C#N)CC1

InChI Key InChIKey=WRCIAIDMFLNHQO-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263413   

TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263413(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']...)
Affinity DataEC50:  490nMAssay Description:Agonist activity at muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263413(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263413(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263413(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263413(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed