BDBM50263886 2-[4-(5-Chloro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-[1,4']bipiperidinyl-1'-ylmethyl]-benzonitrile::CHEMBL491208

SMILES Clc1ccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4C#N)CC3)c(=O)[nH]c2c1

InChI Key InChIKey=FVBQJCJEQPAJFJ-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263886   

TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263886(2-[4-(5-Chloro-2-oxo-2,3-dihydro-benzoimidazol-1-y...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263886(2-[4-(5-Chloro-2-oxo-2,3-dihydro-benzoimidazol-1-y...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263886(2-[4-(5-Chloro-2-oxo-2,3-dihydro-benzoimidazol-1-y...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263886(2-[4-(5-Chloro-2-oxo-2,3-dihydro-benzoimidazol-1-y...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263886(2-[4-(5-Chloro-2-oxo-2,3-dihydro-benzoimidazol-1-y...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed