BDBM50263893 4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bipiperidinyl-4-yl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL521914

SMILES Fc1cccc2n(C3CCN(CC3)C3CCN(Cc4ccccc4C(F)(F)F)CC3)c(=O)[nH]c12

InChI Key InChIKey=YCXFJNGLJADSBQ-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263893   

TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263893(4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bi...)
Affinity DataEC50:  1.71nMAssay Description:Agonist activity at muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263893(4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263893(4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263893(4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263893(4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50263893(4-Fluoro-1-[1'-(2-trifluoromethyl-benzyl)-[1,4']bi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed