BDBM50264284 5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile::CHEMBL523659

SMILES CC1(OCC(=O)Nc2ccc(cc12)-c1ccc([nH]1)C#N)c1cccs1

InChI Key InChIKey=JCAYGZSCOFMVQK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264284   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264284(5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrah...)
Affinity DataEC50:  0.700nMAssay Description:Activity at progesterone receptor assessed as alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264284(5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrah...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]progesterone from progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed