BDBM50264314 5-(5-isopropyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile::CHEMBL523825

SMILES CC(C)C1(OCC(=O)Nc2ccc(cc12)-c1ccc(C#N)n1C)c1cccs1

InChI Key InChIKey=OMPAXBGTKFDCJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264314   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264314(5-(5-isopropyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tet...)
Affinity DataIC50: 36.5nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed