BDBM50264353 1-methyl-5-(2-oxo-5,5-diphenyl-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile::CHEMBL521141

SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(c3ccccc3)(c3ccccc3)c2c1)C#N

InChI Key InChIKey=QVCTUHPLHIIYHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264353   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264353(1-methyl-5-(2-oxo-5,5-diphenyl-1,2,3,5-tetrahydrob...)
Affinity DataIC50: 14.3nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264353(1-methyl-5-(2-oxo-5,5-diphenyl-1,2,3,5-tetrahydrob...)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]progesterone from progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed