BDBM50264383 5-(5-ethyl-1-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile::CHEMBL482625

SMILES CCC1(OCC(=O)N(C)c2ccc(cc12)-c1ccc(C#N)n1C)c1cccs1

InChI Key InChIKey=UUVHMWSDFOHHCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264383   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264383(5-(5-ethyl-1-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed