BDBM50264432 5-((5R)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile::CHEMBL521610

SMILES CC[C@]1(OCC(=O)Nc2ccc(cc12)-c1ccc([nH]1)C#N)c1cccs1

InChI Key InChIKey=MVBYGXGTVIRVQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264432   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264432(5-((5R)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-te...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed