BDBM50264612 7-(1H-indol-2-yl)isoindolin-1-one::CHEMBL482621

SMILES O=C1NCc2cccc(-c3cc4ccccc4[nH]3)c12

InChI Key InChIKey=LEXHMAXLGJIDED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264612   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264612(7-(1H-indol-2-yl)isoindolin-1-one | CHEMBL482621)
Affinity DataIC50:  144nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264612(7-(1H-indol-2-yl)isoindolin-1-one | CHEMBL482621)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264612(7-(1H-indol-2-yl)isoindolin-1-one | CHEMBL482621)
Affinity DataIC50:  100nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed