BDBM50264614 7-(5-methoxy-1H-benzo[d]imidazol-2-yl)isoindolin-1-one::CHEMBL507927

SMILES COc1ccc2nc([nH]c2c1)-c1cccc2CNC(=O)c12

InChI Key InChIKey=NWJXSQTVATYZMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264614   

TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264614(7-(5-methoxy-1H-benzo[d]imidazol-2-yl)isoindolin-1...)
Affinity DataIC50:  205nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264614(7-(5-methoxy-1H-benzo[d]imidazol-2-yl)isoindolin-1...)
Affinity DataIC50:  142nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed