BDBM50264974 (S)-5-fluoro-1-(4-(3-(3-isopropylpyrrolidin-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole::CHEMBL521566

SMILES CC(C)[C@@H]1CCN(CCCOc2ccc(cc2)-n2c(nc3cc(F)ccc23)-c2ccccn2)C1

InChI Key InChIKey=SCAVCNGNYHPFKS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264974   

TargetHistamine H3 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50264974((S)-5-fluoro-1-(4-(3-(3-isopropylpyrrolidin-1-yl)p...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50264974((S)-5-fluoro-1-(4-(3-(3-isopropylpyrrolidin-1-yl)p...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human ERG assessed as rubidium efflux at 5 ug/mL pre-equilibrated for 30 mins by DiBAC4(3)-based flame atomic absorbance spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed