BDBM50265033 CHEMBL522579::N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide
SMILES Cc1nnc(o1)-c1ccc(c(C)c1)-c1cc(ccc1C)C(=O)NC1CC1
InChI Key InChIKey=UBVTVSINEVHYSY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50265033
Affinity DataKi: 10nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MEK1 by cRaf/mek/Erk cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair