BDBM50265097 3-fluoro-4-(4-(5-(methylsulfonyl)-2-(piperidin-1-yl)benzoyl)piperazin-1-yl)benzonitrile::CHEMBL497998

SMILES CS(=O)(=O)c1ccc(N2CCCCC2)c(c1)C(=O)N1CCN(CC1)c1ccc(cc1F)C#N

InChI Key InChIKey=NOSLURAXCPEKTG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265097   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265097(3-fluoro-4-(4-(5-(methylsulfonyl)-2-(piperidin-1-y...)
Affinity DataEC50:  12nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed