BDBM50265242 3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2,4-oxadiazol-5(2H)-one::CHEMBL497151

SMILES Ic1ccc(Oc2cncc3sc(cc23)-c2nc(=O)o[nH]2)cc1

InChI Key InChIKey=KYACBMRLQMEIAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265242   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265242(3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265242(3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of MAP3K8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed

TargetSerine/threonine-protein kinase Nek4(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50265242(3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed