BDBM50265267 1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one::CHEMBL497569

SMILES O=C1OC2(CCN(CC2)c2nc3cc(ccc3[nH]2)-c2ccccc2)c2ccccc12

InChI Key InChIKey=XWIYQJNKTWPXSF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50265267   

TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human NPY Y5 receptor transfected in mouse LMtk cells assessed as inhibition of neuropeptide Y-induced increase in intercellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: 2.40nMAssay Description:Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to NPY Y4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to NPY Y1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50265267(1'-(5-phenyl-1H-benzo[d]imidazol-2-yl)-3H-spiro[is...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to NPY Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed