BDBM50266526 CHEMBL4104267

SMILES CN1CCN(CC1)c1nc(N2CCOCC2)c2sc(CO)cc2n1

InChI Key InChIKey=ONYUTRBXTXRRQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266526   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50266526(CHEMBL4104267)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) expressed in baculovirus infected Sf21 insect cells assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50266526(CHEMBL4104267)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus using PIP2 as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed