BDBM50267577 CHEMBL489640::N6-((+/-)-endo-norborn-2-yl)adenosine

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CC4CCC3C4)ncnc12

InChI Key InChIKey=YKPCEENRZZBDMC-STHLEMNDSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50267577   

TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity against adenosine A1 receptor using N6-[3H]cyclohexyladenosine as radioligand in guinea pig forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity against Adenosine A1 receptor using [3H]CHA in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of N6-[3H]cyclohexyladenosine binding to guinea pig forebrain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity against Adenosine A1 receptor using N6-[3H]cyclohexyladenosine in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  0.910nMAssay Description:Binding affinity against Adenosine A1 receptor using N6-[3H]cyclohexyladenosine in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]HEMADO from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a/A2b(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  750nMAssay Description:Binding affinity against Adenosine A2 receptor using [3H]NECA with 50 nM CPA in rat striatal brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50267577(CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosi...)
Affinity DataKi:  4.93E+3nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed