BDBM50267988 (+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methyloxy)phenyl]ethyl)-amino)-2-hydroxypropyl]oxy)benzonitrile::CHEMBL523475

SMILES COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2C#N)cc1

InChI Key InChIKey=MVYOBBWPCHPRSG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50267988   

TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  34nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  3.60E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  1.00E+3nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50:  76nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed